3 products were found matching "2730-71-4"!
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Thiocolchicine
Item number: TGM-T41248-100mg
Description: Thiocolchicine is an effective inhibitor of tubulin polymerization with an IC50 of 2.5 µM and a Ki of 0.7 µM. Thiocolchicine induces cell apoptosis. Thiocolchicine can be used as an ADC cytotoxin in ADC technology. Target: Microtubule Associated. Smiles:...
| Application: | Apoptosis Inducer |
| CAS | 2730-71-4 |
| MW: | 415.5 D |
From 42.00€
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Thiocolchicine
Item number: Cay17427-10
Thiocolchicine is an inhibitor of microtubule assembly (IC50 = 2.5 µM) and a derivative of colchicine (Cay-9000760). It inhibits binding of colchicine to tubulin (Ki = 0.7 µM in a radioligand binding assay). Thiocolchicine inhibits proliferation of MDA-MB-231 and multidrug resistant (MDR) MCF-7 ADRr breast cancer...
| Keywords: | NSC 186301, N-[(7S)-5,6,7,9-tetrahydro-1,2,3-trimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-7-yl]-acetamide |
| Application: | Tubulin polymerization inhibitor, Topo I inhibitor, apoptosis inducer |
| CAS | 2730-71-4 |
| MW: | 415.5 D |
From 53.00€
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Thiocolchicine
Item number: AG-CN2-0074-M005
Antimitotic alkaloid. Tubulin polymerization and microtubule assembly inhibitor. Axonal cytoskeleton modulator. Apoptosis inducer. Thiocolchicine-dimers were shown to be potent topoisomerase I inhibitors.
| Keywords: | 10-Demethoxy-10-methylthiocolchicine, NSC 186301 |
| Application: | Apoptosis Inducer |
| Host: | Semisynthetic |
| CAS | 2730-71-4 |
| MW: | 415,5 D |
From 39.00€
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