2 products were found matching "2714434-21-4"!

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Item number: Cay45726-1

IAG933 is an inhibitor of the protein-protein interaction between YAP/TAZ and TEAD (IC50 = 8.6 nM in a TR-FRET assay), downstream effectors of Hippo/MST1/2 signaling, which regulates cell proliferation and is frequently dysregulated in cancer. It reduces growth of Hippo-dependent NCI-H2052 mesothelioma cells and...

Keywords:	4S-[(2S)-5-chloro-6-fluoro-2,3-dihydro-2-phenyl-2-(2S)-2-pyrrolidinyl-4-benzofuranyl]-5-fluoro-6-(2-hydroxyethoxy)-N-methy...
Application:	YAP/TAZ-TEAD protein-protein interaction inhibitor
CAS	2714434-21-4
MW:	529.97 D

From 452.00€ *

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YAP-TEAD-IN-3

Item number: TGM-T77725-100mg

Description: YAP-TEAD-IN-3 is an inhibitor of YAP/TAZ-TEAD interactions with an IC50 of 9 nM for Avi-human TEAD (4217-434). YAP-TEAD-IN-3 inhibits YAP reporter gene expression (IC50 = 0.048 µM) and NCI-H2052 cell proliferation (IC50 = 0.048 µM). Target: YAP. Smiles:...

Keywords:	IAG933
CAS	2714434-21-4
MW:	529.96 D

From 310.00€ *

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