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Item number: Cay26071-100

Penfluridol is a first generation typical antipsychotic that binds to dopamine receptors (IC50 = 5.6 nM). It binds to dopamine D4 receptors and also to serotonin (5-HT) receptors (Kis = 31 and 63.1 nM, respectively). Penfluridol (1.25 and 2.5 mg/kg) inhibits stereotypic behavior induced by apomorphine (Cay-16094) in...

Keywords:	R-16341, 1-[4,4-bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]-4-piperidinol
Application:	Calcium channel T type blocker, dopamine D4 receptor ligand, serotonin (5-HT) receptor ligand
CAS	26864-56-2
MW:	524 D

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