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ZG-2033

Item number: Cay41672-1

ZG-2033 is an agonist of hypoxia-inducible factor 2alpha (HIF-2alpha). It induces HIF-2alpha transcriptional activity in a reporter assay using 786-O cells expressing HIF-2alpha (EC50 = 0.49 µM). ZG-2033 (10 or 50 µM), in combination with the inhibitor of hypoxia-inducible factor prolyl hydroxylase 2 (HIF-PH2) and...

Keywords:	N-(3,5-dimethoxyphenyl)-1,2-benzisothiazol-3-amine
Application:	HIF-2alpha (EPAS1) agonist
CAS	2685739-28-8
MW:	286.3 D

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