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RBPJ Inhibitor-1
RBPJ Inhibitor-1

Item number: Cay43358-10

RBPJ inhibitor-1 is an inhibitor of recombination signal binding protein for immunoglobulin kappa J region (RBPJ, IC50 = 0.18 µM in a reporter assay). It also inhibits the protein-protein interaction between RBPJ and the neurogenic locus notch homolog protein 2 (Notch2) intracellular domain (NICD) and the...
Keywords: RIN1, 2-(2-fluorophenoxy)-4-(1-methyl-1H-pyrazol-5-yl)-benzamide
Application: RBPJ inhibitor
CAS 2682114-39-0
MW: 311.32 D
From 146.00€ *
Review
RBPJ Inhibitor-1
RBPJ Inhibitor-1

Item number: TGM-T35566-100mg

Description: RBPJ Inhibitor-1 (RIN1), a compound that impedes the functional interaction between RBPJ and SHARP, effectively inhibits NOTCH-dependent tumor cell proliferation[1]. Target: Gamma-secretase. Smiles: O(C1=C(C(N)=O)C=CC(=C1)C=2N(C)N=CC2)C3=C(F)C=CC=C3. References: Hurtado C, et al. Disruption of NOTCH...
Keywords: RIN1
Application: RBPJ inhibitor
CAS 2682114-39-0
MW: 311.31 D
From 33.00€ *
Review