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Item number: SYN-1030-M010

Soluble in DMSO or ethanol. Canertinib is an orally bio-available EGFR inhibitor with potential anti-neoplastic and radio-sensitizing activities. It has IC(50) values of 1.5nM and 9.0nM against EGFR and ErbB2 respectively, with no activity against PDGFR, FGFR, InsR, PKC, or CDK1/2/4. Target: EGFR , Kinase Group:...

Keywords:	CI1033, PD-183805
Application:	EGFR inhibitor
CAS	267243-28-7
MW:	486 D

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Canertinib

Item number: TGM-T6136-5mg

Description: Canertinib (CI-1033) is a pan-erbB tyrosine kinase inhibitor which work against esophageal squamous cell carcinoma in vitro and in vivo. Canertinib treatment significantly affects tumour metabolism, proliferation and hypoxia as determined by PET. Target: EGFR. Smiles:...

Keywords:	CI-1033, PD-183805
Application:	EGFR inhibitor
CAS	267243-28-7
MW:	485.94 D

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