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Item number: TGM-T15233-100mg

Description: Endovion (NS3728) is a pharmacological anion channel and an Anoctamin-1 (ANO 1) channel inhibitor. Endovion is also the specific VRAC/VSOAC blocker. Target: Chloride channel. Smiles: FC(F)(F)c1cc(NC(=O)Nc2ccc(Br)cc2-c2nn[nH]n2)cc(c1)C(F)(F)F. References: Sørensen BH, et al. Downregulation of LRRC8A...

Keywords:	NS3728
Application:	Chloride channel inhibitor
CAS	265646-85-3
MW:	495.18 D

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NS 3728

Item number: Cay39988-10

NS 3728 is a chloride channel inhibitor. It inhibits the volume-regulated anion channel (VRAC) in HEK293 cells and chloride conductance in washed isolated human erythrocytes (IC50s = 0.4 and 0.6 µM, respectively). NS 3728 also inhibits calcium-activated chloride currents in Ehrlich-Lettre ascites carcinoma cells...

Keywords:	Endovion, SCO 101, N-[3,5-bis(trifluoromethyl)phenyl]-N'-[4-bromo-2-(2H-tetrazol-5-yl)phenyl]-urea
Application:	Chloride channel inhibitor
CAS	265646-85-3
MW:	495.2 D

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