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2-(1-(3-(2,4-Dioxotetrahydropyrimidin-1(2H)-yl)-5-fluoro-1-methyl-1H-indazol-6-yl)-4-hydroxypiperidi
2-(1-(3-(2,4-Dioxotetrahydropyrimidin-1(2H)-yl)-5-fluoro-...

Item number: Cay45721-10

2-(1-(3-(2,4-Dioxotetrahydropyrimidin-1(2H)-yl)-5-fluoro-1-methyl-1H-indazol-6-yl)-4-hydroxypiperidin-4-yl)acetic acid is a proteolysis-targeting chimera (PROTAC) building block. It has been used in the synthesis of a PROTAC that drives mutant B-RAF degradation.. SMILES:...
Keywords: 1-[5-fluoro-1-methyl-3-(tetrahydro-2,4-dioxo-1(2H)-pyrimidinyl)-1H-indazol-6-yl]-4-hydroxy-4-piperidineacetic acid
Application: PROTAC building block
CAS 2654826-81-8
MW: 419.41 D
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