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CYY292
Item number: TGM-T83911-10mg
Description: CYY292 is a chemical compound acting as an inhibitor of PDGFRalpha, PDGFRbeta, FGFR1, -2, and -3, with respective IC50 values of 5.35, 4.6, 28, 28, and 78 nM. It exhibits selectivity over FGFR4 (IC50 > 1,000 nM) while also targeting c-Kit, VEGFR2, VEGFR1, and IGF-1R (IC50 values of 67, 33, 36, and 75...
| Application: | PDGFR/FGFR inhibitor |
| CAS | 2644673-04-9 |
| MW: | 444.53 D |
From 122.00€
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CYY292
Item number: Cay39831-1
CYY292 is an inhibitor of PDGFRalpha, PDGFRbeta, FGFR1, -2, and -3, (IC50s = 5.35, 4.6, 28, 28, and 78 nM, respectively). It is selective for these kinases over FGFR4 (IC50 = >1,000 nM) but also inhibits c-Kit, VEGFR2, VEGFR1, and insulin-like growth factor 1 receptor (IGF-1R, IC50s = 67, 33, 36, and 75 nM,...
| Keywords: | N4-1H-indazol-6-yl-N2-[3-methoxy-4-(4-methyl-1-piperazinyl)phenyl]-5-methyl-2,4-pyrimidinediamine |
| Application: | PDGFR/FGFR inhibitor |
| CAS | 2644673-04-9 |
| MW: | 444.5 D |
From 54.00€
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