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Item number: Cay14720-1

15-keto Prostaglandin E2 (15-keto PGE2) is a metabolite of PGE2 (Cay-14010) formed by 15-hydroxy prostaglandin dehydrogenase (15-PGDH). Unlike PGE2, 15-keto PGE2 does not bind effectively to the PGE2 receptors EP2 and EP4 expressed in CHO cells (Kis = 2.6 and 15 µM, respectively) or induce adenylate cyclase activity...

Keywords:	15-keto PGE2, 15-keto-PGE2, 9,15-dioxo-11alpha-hydroxy-prosta-5Z,13E-dien-1-oic acid
Application:	Bioactive lipid assays
CAS	26441-05-4
MW:	350.5 D

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15-keto-Prostaglandin E2

Item number: TGM-T78582-25mg

Description: 15-keto-Prostaglandin E2, an endogenous metabolite, inhibits STAT3 activation through binding to Cys259 and regulates breast cancer cell growth and progression. Additionally, it binds and stabilizes the EP2 and EP4 receptors, activates PPAR-gamma, and promotes fungal growth [1] [2] [3]. Target:...

Keywords:	15-keto-PGE2
CAS	26441-05-4
MW:	350.45 D

8,713.00€ *

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