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15-keto Prostaglandin E2
15-keto Prostaglandin E2

Item number: Cay14720-1

15-keto Prostaglandin E2 (15-keto PGE2) is a metabolite of PGE2 (Cay-14010) formed by 15-hydroxy prostaglandin dehydrogenase (15-PGDH). Unlike PGE2, 15-keto PGE2 does not bind effectively to the PGE2 receptors EP2 and EP4 expressed in CHO cells (Kis = 2.6 and 15 µM, respectively) or induce adenylate cyclase activity...
Keywords: 15-keto PGE2, 9,15-dioxo-11alpha-hydroxy-prosta-5Z,13E-dien-1-oic acid
Application: Bioactive lipid assays
CAS 26441-05-4
MW: 350.5 D
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