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CID-2745687
Item number: Cay12046-10
GPR35 is a G protein-coupled receptor that is activated by kynurenic acid and 2-acyl lysophosphatidic acids (e.g., 2-oleoyl lysophosphatidic acid). It is expressed predominantly on immune cells, the brain, and in the gastrointestinal tract. GPR35 is overexpressed in gastric cancer cells. CID-2745687 is a reversible,...
| Keywords: | ML-194,... |
| Application: | GPR35 antagonist |
| CAS | 264233-05-8 |
| MW: | 395.4 D |
From 128.00€
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CID 2745687
Item number: TGM-T21874-100mg
Description: CID 2745687 is a GPR35 antagonist that inhibited the effects at human GPR35 of cromolyn disodium and zaprinast, two agonists that share an overlapping binding site. Target: GPR. Smiles: COC(=O)c1cnn(c1C=NNC(=S)NC(C)(C)C)-c1ccc(F)cc1F. References: Jenkins L , Harries N , Lappin J E , et al. Antagonists...
| CAS | 264233-05-8 |
| MW: | 395.43 D |
From 34.00€
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