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GR148672X
GR148672X

Item number: Cay28756-1

GR148672X is an inhibitor of triacylglycerol hydrolase/carboxylesterase 1 (TGH/CES1, IC50 = 4 nM for the human hepatic enzyme). It is selective for TGH/CES1 over lipoprotein lipase (LPL) at 5 µM. GR148672X (25 mg/kg twice per day) decreases plasma levels of triglycerides, total, VLDL, and LDL cholesterol, and...
Keywords: 4,4,4-trifluoro-1-(2-thienyl)-1,2,3-butanetrione, 2-[(3-methylphenyl)hydrazone]
Application: TGH/CES1 inhibitor
CAS 263890-70-6
MW: 340.3 D
From 102.00€ *
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GR148672X
GR148672X

Item number: TGM-T15416-100mg

Description: GR148672X is an inhibitor of triacyglycerol hydrolase (TGH) (IC50: 4 nM). Target: Others. Smiles: Cc1cccc(N\N=C(\C(=O)c2cccs2)C(=O)C(F)(F)F)c1. References: Catherine Sylvia Borg-Capra, et al. Method of screening for triacyglycerol hydrolase inhibitors . WO 2001016358 A2.
Application: TGH/CES1 inhibitor
CAS 263890-70-6
MW: 340.32 D
From 39.00€ *
Review