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COVID-19 Research
PF-07321332
PF-07321332

Item number: Cay35257-1

PF-07321332 is an orally bioavailable inhibitor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (Mpro), also known as 3C-like protease (3CLpro), with a Ki value of 3.11 nM. It also inhibits Mpro from other members of the Betacoronavirus genus, including SARS-CoV-1, HKU1-CoV, OC43-CoV,...
Keywords: Nirmatrelvir,...
Application: SARS-CoV-2 Mpro inhibitor
CAS 2628280-40-8
MW: 499.5 D
From 133.00€ *
Review
Nirmatrelvir
Nirmatrelvir

Item number: TGM-T9351-5mg

Description: PF-07321332 is a potent and orally active inhibitor of SARS-CoV 3C-like protease (3CLPRO) . Target: SARS-CoV. Smiles: C(N[C@@H](C[C@H]1C(=O)NCC1)C#N)(=O)[C@@H]2[C@@]3([C@@](C3(C)C)(CN2C([C@@H](NC(C(F)(F)F)=O)[C@](C)(C)C)=O)[H])[H]. References: Li J, et al. Nirmatrelvir exerts distinct antiviral potency...
Application: Targets SARS coronavirus 3C-like proteinase [EC:3.4.22.69] (nsp5)
CAS 2628280-40-8
MW: 499.53 D
From 50.00€ *
Review