3 products were found matching "2621928-55-8"!
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MRTX1133
Item number: TGM-T9303-100mg
Description: MRTX1133 is a KRAS G12D inhibitor (KD=0.2 pM) that is potent, selective, and non-covalent. MRTX1133 exhibits inhibitory activity against KRAS G12D-mutated tumors, but not against KRAS wild-type tumors. Target: Ras. Smiles:...
| Application: | RAS G12D inhibitor |
| CAS | 2621928-55-8 |
| MW: | 600.63 D |
From 195.00€
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MRTX-1133
Item number: Cay36413-1
MRTX-1133 is an inhibitor of K-RasG12D, a mutant form of K-Ras that accumulates in cancer cells. It selectively reduces ERK phosphorylation in AsPC-1 cells expressing mutant K-RasG12D (IC50 = 10.8 nM) over MiaPaCa-2 and SW620 cells expressing mutant K-RasG12C or K-RasG12V (IC50s = 456 and 4,400 nM, respectively) and...
| Keywords: | 4-[4-(3,8-diazabicyclo[3.2.1]oct-3-yl)-8-fluoro-2-[[(2R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy]pyrido[4,3... |
| Application: | K-RasG12D inhibitor |
| CAS | 2621928-55-8 |
| MW: | 600.6 D |
From 111.00€
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MRTX1133
Item number: LKT-M704789.1
MRTX113 is a potent and selective inhibitor of KRASG12D protein. SMILES: C#CC1=C(C=CC2=CC(=CC(=C21)C3=NC=C4C(=C3F)N=C(N=C4N5CC6CCC(C5)N6)OCC78CCCN7CC(C8)F)O)F
| Keywords: | NSC-836407,... |
| Application: | KRAS inhibitor |
| CAS | 2621928-55-8 |
| MW: | 600.65 D |
From 145.00€
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