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Item number: Cay17081-10

The transduction of neurobehavioral effects by serotonin (5-hydroxy tryptamine, 5-HT) is mediated by at least seven major 5-HT receptor subtypes. SB-269970 is a potent 5-HT7A antagonist (pKi = 8.9) that demonstrates >50-fold binding selectivity over 5-HT5A and >250-fold selectivity over 5-HT1, 5-HT2, 5-HT4, 5-HT6,...

Keywords:	3-[[(2R)-2-[2-(4-methyl-1-piperidinyl)ethyl]-1-pyrrolidinyl]sulfonyl]-phenol, monohydrochloride
Application:	5-HT7A antagonist
CAS	261901-57-9
MW:	389 D

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