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FTI-277 (hydrochloride)
FTI-277 (hydrochloride)

Item number: Cay10011667-10

An FTase inhibitor (IC50 = 0.1 µM), selective for FTase over GGTase (IC50 = >10 µM), inhibits IL-1beta-induced production of NO in primary rat pulmonary artery smooth muscle cells at 10 µM, decreases the proliferation of A549 cells when used at 10 µM and induces cell cycle arrest at the G2/M phase in the same cells...
Keywords: Farnesyltransferase Inhibitor 277, FTase Inhibitor 277,...
Application: Farnesyltransferase inhibitor
CAS 261636-47-9
MW: 447.61 D
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