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Item number: Cay43722-10

XST-14 is an inhibitor of unc-51-like autophagy activating kinase 1 (ULK1, IC50 = 13.6 nM). It is selective for ULK1 over anaplastic lymphoma kinase 2 (ALK2), p38alpha MAPK, TGF-beta receptor type 2 (TGFBR2), and MEK1 (IC50s = 183.8, 283.9, 809.3, and 721.8 nM, respectively) but does inhibit...

Keywords:	4,6-bis(1-methylethoxy)-H-indole-2-carboxylic acid, methyl ester
Application:	ULK1 inhibitor
CAS	2607143-50-8
MW:	291,35 D

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XST-14

Item number: TGM-T60604-10mg

Description: XST-14 is a competitive and specific inhibitor of ULK1 (IC50: 26.6 nM).XST-14 blocks autophagy by inhibiting the phosphorylation of ULK1 downstream substrates.XST-14 induces apoptosis and inhibits the growth of HCC cells. Target: Autophagy, Apoptosis. Smiles: COC(=O)c1cc2c(OC(C)C)cc(OC(C)C)cc2[nH]1....

CAS	2607143-50-8
MW:	291.34 D

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