Description: Z-CITCO acts as an agonist for the constitutive androstane receptor (CAR, with an EC50 of 3.9 µM in human receptor reporter assays) and is the cis isomer of the CAR agonist CITCO. Target: Others. Smiles: ClC(C=C1)=CC=C1C(N=C2N3C=CS2)=C3/C=N\OCC4=CC(Cl)=C(Cl)C=C4

Z-CITCO is an agonist of the constitutive androstane receptor (CAR, EC50 = 3.9 µM for the human receptor in a reporter assay) and the cis isomer of the CAR agonist CITCO (Cay-16027).Formal Name: [C(Z)]-6-(4-chlorophenyl)-imidazo[2,1-b]thiazole-5-carboxaldehyde O-[(3,4-dichlorophenyl)methyl]oxime. CAS Number:...