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NX-1607
Item number: Cay45222-1
An inhibitor of Cbl-b (IC50 = 3.4 nM), increases IL-2 secretion in primary human T cells (EC50 = 180.6 nM), application of NX-1607 to anti-CD19 CAR-T cells generated from patients with DLBCL increases the number of CAR-T cells formed during expansion, increases the production of IFN-gamma, TNF-alpha, IL-2, and...
| Keywords: | Cbl-b-IN-3,... |
| Application: | E3 ubiquitin-protein ligase CBL-B inhibitor |
| CAS | 2573775-59-2 |
| MW: | 537.63 D |
From 64.00€
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Cbl-b-IN-3
Item number: TGM-T63790-100mg
Description: Cbl-b-IN-3 is a potent inhibitor of casitas b lineage lymphoma proto-oncogene-b (Cbl-b) (ic50 < 1 nM). Target: E1/E2/E3 Enzyme. Smiles: CN1C([C@]2(C[C@@H](C)C2)C3=CC(=CC=C3)N4CC=5C(C4=O)=CC(CN6C[C@@H](C)CCC6)=CC5C(F)(F)F)=NN=C1. References: Arthur T. Sands, et al. Substituted benzyl-triazole compounds...
| CAS | 2573775-59-2 |
| MW: | 537.62 D |
From 60.00€
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