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Item number: TGM-T21712-100mg

Description: BAY 41-8543 is a nitric oxide (NO)-independent stimulator of soluble guanylyl cyclase (sGC). Target: Guanylate cyclase, Others. Smiles: Nc1nc(nc(N)c1N1CCOCC1)-c1nn(Cc2ccccc2F)c2ncccc12. References: Badejo A M , Nossaman V E , Pankey E A , et al. Pulmonary and systemic vasodilator responses to the...

CAS	256498-66-5
MW:	420.44 D

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BAY 41-8543

Item number: Cay10011131-10

Soluble guanylate cyclase (sGC) is the primary cellular receptor for nitric oxide (NO). NO binds and activates a heme group in sGC, initiating the conversion of GTP to the second messenger cyclic GMP (cGMP). BAY 41-8543 is a heme-dependent stimulator of sGC, increasing the activity of recombinant sGC...

Keywords:	2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-(4-morpholinyl)-4,6-pyrimidinediamine
Application:	SGC stimulator
CAS	256498-66-5
MW:	420.4 D

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