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Item number: Cay44250-1

Garsorasib is an inhibitor of K-Ras containing the activating glycine-to-cysteine mutation at position 12 (K-RasG12C, IC50 = 18 nM). It selectively binds to GDP-bound K-RasG12C over GDP-bound wild-type K-Ras in thermal shift assays and selectively inhibits ERK phosphorylation in NCI H358 cells, which express...

Keywords:	D-1553, 7-(2-amino-6-fluorophenyl)-1-(4,...
Application:	K-RasG12C inhibitor
CAS	2559761-14-5
MW:	598,66 D

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