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Item number: Cay45992-10

Apostatin-1 is an inhibitor of the protein-protein interaction between TNFR1-associated DEATH domain protein (TRADD) and TNF receptor-associated factor 2 (TRAF2). It selectively binds to the N-terminal of TRADD (Kd = 2.17 µM) over a panel of 97 kinases at 10 µM. Apostatin-1 inhibits bortezomib-induced apoptosis in...

Keywords:	Apt-1, N-cycloheptyl-alpha-[(4,5-dihydro-1-methyl-1Himidazol-2-yl)thio]-benzeneacetamide
Application:	TRADD-TRAF2 protein-protein interaction inhibitor
CAS	2559703-06-7
MW:	345.5 D

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Apostatin-1

Item number: TGM-T9079-100mg

Description: Apostatin-1 (Apt-1) is a novel TRADD inhibitor that binds to a pocket on the N-terminal TRAF2 binding domain of TRADD. Target: Others. Smiles: CN1CCN=C1SC(C(=O)NC1CCCCCC1)c1ccccc1. References: Xu D , Zhao H , Jin M , et al. Modulating TRADD to restore cellular homeostasis and inhibit apoptosis[J]....

Keywords:	Apt-1
CAS	2559703-06-7
MW:	345.5 D

From 30.00€ *

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