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Item number: Cay15578-1

The two isoforms of glycogen synthase kinase 3, GSK3alpha and GSK3beta, constitutively phosphorylates and inactivates glycogen synthase, preventing glycogen synthesis. They also phosphorylate proteins that are relevant to Alzheimer's disease and osteogenesis. CHIR98014 is a reversible, cell-permeable inhibitor of...

Keywords:	N6-[2-[[4-(2,4-dichlorophenyl)-5-(1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]-3-nitro-2,6-pyridinediamine
Application:	GSK3alpha / GSK3beta inhibitor
CAS	252935-94-7
MW:	486.3 D

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CHIR-98014

Item number: TGM-T2608-100mg

Description: CHIR-98014 (CT98014) is a selective GSK3 inhibitor, potentiate insulin activation of glucose transport and utilization in vitro and in vivo. Target: Src, GSK-3, FGFR, S6 Kinase. Smiles: ClC1=C(C=2C(=CN=C(NCCNC=3N=C(N)C(N(=O)=O)=CC3)N2)N4C=CN=C4)C=CC(Cl)=C1. References: Ring DB,et al. Diabetes. 2003,...

Keywords:	CHIR98014, CHIR 98014, CT98014
Application:	GSK3alpha / GSK3beta inhibitor
CAS	252935-94-7
MW:	486.31 D

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