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A-205804
Item number: Cay21252-1
A-205804 is a potent inhibitor of E-selectin and ICAM-1 expression in human vascular endothelial cells stimulated with TNF-alpha (IC50s = 20 and 25 nM, respectively). It does not block expression of VCAM-1 (IC50 > 1,000 nM).Formal Name: 4-[(4-methylphenyl)thio]-thieno[2,3-c]pyridine-2-carboxamide. CAS Number:...
| Keywords: | 4-[(4-methylphenyl)thio]-thieno[2,3-c]pyridine-2-carboxamide |
| Application: | E-selectin & ICAM-1 expression inhibitor |
| CAS | 251992-66-2 |
| MW: | 300.4 D |
From 49.00€
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A-205804
Item number: TGM-T2254-100mg
Description: A-205804 is a specific and effective inhibitor of E-selectin( IC50=20 nM ) and ICAM-1(IC50=25 nM) expression. Target: Integrin. Smiles: Cc1ccc(Sc2cncc3sc(cc23)C(N)=O)cc1. References: Zhu GD, et al. J Med Chem, 2001, 44(21), 3469-3487.
| Application: | E-selectin & ICAM-1 expression inhibitor |
| CAS | 251992-66-2 |
| MW: | 300.4 D |
From 36.00€
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