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YAP/TAZ Inhibitor-3
YAP/TAZ Inhibitor-3

Item number: Cay45146-1

An inhibitor of the TEAD-YAP/TAZ protein-protein interaction, inhibits TEAD1-4 palmitoylation in HEK293T cells expressing TEAD1-4 at 3 µM, inhibits the proliferation of a variety of mesothelioma cells, including those with homozygous expression of NF2 mutations (GI50s = 8-74 nM) or heterozygous expression of NF2...
Keywords: VT3989, N-[(1R)-2-hydroxy-1-methylethyl]-5-[4-(trifluoromethyl)phenoxy]-2-naphthalenecarboxamide
Application: TEAD-YAP/TAZ protein-protein interaction inhibitor
CAS 2506273-81-8
MW: 389.37 D
From 203.00€ *
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