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CFT7455
CFT7455

Item number: TGM-T60024-10mg

Description: CFT7455 (Cemsidomide) is an anti-cancer agent showing high affinity to the cereblon E3 ligase with a Kd of 0.9 nM. CFT7455 is an orally active degrader of zinc finger transcription factors Ikaros (IKZF1), and Aiolos (IKZF3). Target: Ligand for E3 Ligase. Smiles:...
Keywords: Cemsidomide
Application: Protac(R) reagent
CAS 2504235-67-8
MW: 469.53 D
From 75.00€ *
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CFT7455
CFT7455

Item number: BPS-82010

CFT7455 is an anti-cancer agent that binds with high affinity to the cereblon E3 ligase.
Application: Protac(R) reagent
CAS 2504235-67-8
MW: 469,5 D
2,100.00€ *
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CFT-7455
CFT-7455

Item number: Cay42053-1

A cereblon ligand 1-containing degrader of IKZF1 and IKZF3, reduces levels of IKZF1 and IKZF3 in NCI H929 cells at 0.1 nM, decreases the growth of NCI H929 cells (GI50 = 0.0743 nM), reduces tumor volume in an RPMI-8226 plasmocytoma mouse xenograft model at 30 or 100 µg/kg per day. Formulation: A solid. InChI:...
Keywords: Cemsidomide, 3S-[6-[[4-(4-morpholinylmethyl)phenyl]methyl]-2-oxobenz[cd]indol-1(2H)-yl]-2,6-piperidinedione
Application: Cereblon ligand 1-containing IKZF1 / IKZF3 degrader
CAS 2504235-67-8
MW: 469.53 D
From 110.00€ *
Review