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Item number: TGM-T9060-10mg

Description: STM2457 is an inhibitor of the RNA methyltransferase METTL3 (IC50=16.9 nM) with selective and oral activity.STM2457 can be used in acute myeloid leukemia (AML) studies. Target: Apoptosis, Others. Smiles: O=C(NCc1cn2cc(CNCC3CCCCC3)ccc2n1)c1cc(=O)n2ccccc2n1. References: Yankova E, et al. Small-molecule...

Application:	The METTL3/14 complex inhibitor
CAS	2499663-01-1
MW:	444.53 D

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STM2457

Item number: Cay34280-10

STM2457 is an inhibitor of the methyltransferase-like 3 (METTL3) and METTL14 complex (IC50 = 16.9 µM). It inhibits growth in a panel of acute myeloid leukemia (AML) cell lines (IC50s = 0.6-10.3 µM). STM2457 also inhibits the proliferation, migration, and invasion of HuCC-T1 and HCCC-9810 intrahepatic...

Keywords:	N-[[6-[[(cyclohexylmethyl)amino]methyl]imidazo[1,2-a]pyridin-2-yl]methyl]-4-oxo-4H-pyrido[1,2-a]pyrimidine-2-carboxamide
Application:	The METTL3/14 complex inhibitor
CAS	2499663-01-1
MW:	444.5 D

From 112.00€ *

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