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SB-328437
SB-328437

Item number: Cay29677-1

SB-328437 is a nonpeptide chemokine (C-C motif) receptor 3 (CCR3) antagonist (IC50 = 4.5 nM in a radioligand binding assay). It is selective for CCR3 over chemokine (C-X-C motif) receptor 1 (CXCR1), CXCR2, CCR7, complement 3a receptor (C3aR), and C5aR (IC50s = >27, >27, >33, >10, and >10 µM, respectively). SB-328437...
Keywords: N-(1-naphthalenylcarbonyl)-4-nitro-L-phenylalanine, methyl ester
Application: CCR3 antagonist
CAS 247580-43-4
MW: 378.4 D
From 52.00€ *
Review
SB 328437
SB 328437

Item number: TGM-T23321-100mg

Description: SB 328437 ((S)-methyl 2-(1-naphthamido)-3-(4-nitrophenyl)propanoate) is an effective and selective antagonist of CCR3 (IC50 = 4.5 nM). Target: CCR. Smiles: COC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12
Keywords: (S)-methyl 2-(1-naphthamido)-3-(4-nitrophenyl)propanoate , ZINC29222893
Application: CCR3 antagonist
CAS 247580-43-4
MW: 378.38 D
From 34.00€ *
Review