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Item number: Cay35055-1

Apatinib-d8 is intended for use as an internal standard for the quantification of apatinib (Cay-21268) by GC- or LC-MS. Apatinib is a tyrosine kinase inhibitor that potently suppresses the kinase activity of vascular endothelial growth factor 2 (VEGFR2, IC50 = 1 nM). It is less effective against c-Kit (IC50 = 429...

Keywords:	N-[4-(1-cyanocyclopentyl-2,2,3,3,4,4,5,5-d8)phenyl]-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide
Application:	GC-MS, LC-MS internal standard, quantification, VEGFR2 inhibitor
CAS	2468771-43-7
MW:	405.5 D

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Apatinib-d8

Item number: TGM-TMID-0288-1mg

Description: Apatinib-d8 is a deuterated compound of Apatinib. Apatinib has a CAS number of 811803-05-1. Apatinib is an orally bioavailable and specific VEGFR2 inhibitor (IC50: 1 nM). In addition, this agent mildly inhibits c-Kit and c-SRC tyrosine kinases. Smiles:...

Application:	GC-MS, LC-MS internal standard, quantification, VEGFR2 inhibitor
CAS	2468771-43-7
MW:	405.52 D

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