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Usnoflast
Item number: Cay45301-1
An NLRP3 inflammasome inhibitor, inhibits ASC oligomerization in LPS-primed and ATP-activated THP-1 cells, reduces nigericin-induced IL-1beta release in LPS-primed THP-1 cells and microglia (IC50s = 11 and 43 nM, respectively), reduces ATP-induced IL-1beta release in LPS-primed human PBMCs (IC50 = 4.5 nM), improves...
| Keywords: | ZYIL1, 2-[(2R)-1E,2-dimethyl-2-pyrrolidinyl]-N-[[(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)amino]carbonyl]-ethenesulfonamide |
| Application: | NLRP3 inflammasome inhibitor |
| CAS | 2455519-86-3 |
| MW: | 403.54 D |
From 624.00€
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Usnoflast
Item number: TGM-T79864-5mg
Description: Usnoflast functions as an NLRP3 modulator and also serves as a non-steroidal anti-inflammatory agent (NSAID) [1]. Target: NOD-like Receptor (NLR)
| CAS | 2455519-86-3 |
| MW: | 403.54 D |
902.00€
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