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Item number: Cay24160-1

DS16570511 is an inhibitor of the mitochondrial calcium uniporter. It inhibits calcium uptake by mitochondria isolated from HEK293A cells, rat heart, and pig heart (IC50s = 0.86, 25, and 15 µM, respectively). DS16570511 inhibits fetal bovine serum-induced mitochondrial calcium influx as well as MCU- and...

Keywords:	3-[3-[[[3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolyl]methyl]amino]benzoyl]-1H-indole-1-butanoic acid
Application:	Mitochondrial calcium uniporter inhibitor
CAS	2446154-84-1
MW:	562.4 D

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DS16570511

Item number: TGM-T11102-100mg

Description: DS16570511 is a novel, cell-permeable inhibitor targeting the mitochondrial calcium uniporter. It effectively blocks the increase in Ca2+ influx dependent on MCU or MICU1 [1]. Target: Calcium Channel. Smiles: C(=O)(C=1C=2C(N(CCCC(O)=O)C1)=CC=CC2)C3=CC(NCC=4C(=NOC4C)C5=C(Cl)C=CC=C5Cl)=CC=C3. References:...

CAS	2446154-84-1
MW:	562.44 D

From 243.00€ *

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