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L-826,266
L-826,266

Item number: Cay18538-1

L-826,266 is a potent and selective competitive antagonist of the prostaglandin E2 receptor subtype EP3 (Ki = 0.8 nM). It also binds to the EP4 receptor (Ki = 715 nM) but does not bind to EP1 or EP2 receptors up to a concentration of 5,000 nM. L-826,266 inhibits vasoconstriction induced by the EP3 agonist...
Keywords: (2E)-N-[(5-bromo-2-methoxyphenyl)sulfonyl]-3-[5-chloro-2-(2-naphthalenylmethyl)phenyl]-2-propenamide
Application: Prostaglandin E2 receptor EP3 subtype competitive antagonist
CAS 244101-03-9
MW: 570.9 D
From 137.00€ *
Review
L-826266
L-826266

Item number: TGM-T27788-100mg

Description: L-826266 is an antagonist of EP(1) receptor. Target: Others. Smiles: COc1ccc(Br)cc1S(=O)(=O)NC(=O)\C=C\c1cc(Cl)ccc1Cc1ccc2ccccc2c1. References: Kozlowska H, Baranowska-Kuczko M, Schlicker E, Kozlowski M, Zakrzeska A, Grzeda E, Malinowska B. EP3 receptor-mediated contraction of human pulmonary arteries...
Keywords: L 826266
Application: Prostaglandin E2 receptor EP3 subtype competitive antagonist
CAS 244101-03-9
MW: 570.88 D
From 1,013.00€ *
Review