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Item number: Cay26068-25

Bufexamac is an NSAID and inhibitor of the class IIb histone deacetylases HDAC6 and HDAC10. It inhibits the production of IFN-alpha in peripheral blood mononuclear cells (PBMCs, EC50 = 8.9 µM). Bufexamac induces hyperacetylation of tubulin (IC50 = 2.9 µM), a major substrate of HDAC6, without increasing acetylation...

Keywords:	4-butoxy-N-hydroxy-benzeneacetamide
Application:	COX inhibitor, HDAC6 / HDAC10 inhibitor
CAS	2438-72-4
MW:	223.3 D

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