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GSK690 (hydrochloride)
Item number: Cay45320-1
GSK690 is a lysine-specific demethylase 1 (LSD1) inhibitor (IC50 = 0.09 µM in a cell-free assay). It is selective for LSD1 over monoamine oxidase A (MAO-A, IC50 = >200 µM). GSK690 inhibits LSD1 activity in THP-1 acute myeloid leukemia cells (IC50 = 1.4 µM). GSK690 potentiates reductions in viability of SJCRH30...
| Keywords: | 4-[2-(4-methylphenyl)-5-[(3R)-3-pyrrolidinylmethoxy]-3-pyridinyl]-benzonitrile, monohydrochloride |
| Application: | Lysine-specific histone demethylase 1A (KDM1A/LSD1) inhibitor |
| CAS | 2436760-79-9 |
| MW: | 405.93 D |
From 69.00€
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GSK 690 Hydrochloride
Item number: TGM-T11503-100mg
Description: GSK 690 (Hydrochloride) is a reversible lysine-specific demethylase 1 (LSD1) inhibitor with a Kd of 9 nM and an IC50 of 37 nM. Target: Histone Demethylase. Smiles: N#CC1=CC=C(C2=CC(OC[C@H]3CNCC3)=CN=C2C4=CC=C(C)C=C4)C=C1.Cl. References: Mould DP, et al. Development of (4-Cyanophenyl)glycine Derivatives...
| CAS | 2436760-79-9 |
| MW: | 405.92 D |
From 1,374.00€
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