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Item number: Cay44470-1

Exatecan-amide-cyclopropanol is a derivative of the DNA topoisomerase I inhibitor exatecan (Cay-35452) that has been used as a building block in the synthesis of antibody-drug conjugates (ADCs) with anticancer activity. Formal Name:...

Keywords:	N-[(1S,9S)-9-ethyl-5-fluoro-2,3,9,10,13,15-hexahydro-9-hydroxy-4-methyl-10,13-dioxo-1H,12H-benzo[de]pyrano[3',4':6,7]indol...
Application:	Exatecan derivative, ADC building block
CAS	2414254-34-3
MW:	519.53 D

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Exatecan-amide-cyclopropanol

Item number: TGM-T63624-25mg

Description: Exatecan-amide-cyclopropanol is an anticancer agent that inhibits the proliferation of SK-BR-3 cells (IC50: 0.12 nM) and U87 cells (IC50: 0.23 nM). Target: Others, ADC Cytotoxin. Smiles: CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4cc(F)c(C)c5CC[C@H](NC(=O)C6(O)CC6)c(c3Cn1c2=O)c45

CAS	2414254-34-3
MW:	519.52 D

From 500.00€ *

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