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![CA77.1 [CMA Activator]](https://www.biomol.com/media/image/21/19/4c/AG-CR1-0165-M005_200x200.png "CA77.1 [CMA Activator]")
CA77.1 [CMA Activator]
Item number: AG-CR1-0165-M005
CA77.1 is a novel selective chaperone-mediated autophagy (CMA) activator by increasing the expression of the lysosomal receptor for this pathway, LAMP2A, in lysosomes. Chaperone-mediated autophagy (CMA), is a selective autophagy shown to degrade neurodegeneration-related proteins such as alpha-synuclein (alpha-syn)...
| Keywords: | N-[4-(6-Chloroquinoxalin-2-yl)phenyl]acetamide |
| Application: | Selective chaperone-mediated autophagy (CMA) activator |
| CAS | 2412270-22-3 |
| MW: | 297,7 D |
From 77.00€
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CA77.1
Item number: TGM-T9062-100mg
Description: CA77.1(CA) is a novel chaperon-mediated autophagy (CMA) activator for the treatment of Alzheimer's disease (AD). Target: Autophagy. Smiles: CC(=O)Nc1ccc(cc1)-c1cnc2cc(Cl)ccc2n1
| Application: | Selective chaperone-mediated autophagy (CMA) activator |
| CAS | 2412270-22-3 |
| MW: | 297.74 D |
From 49.00€
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CA77.1
Item number: Cay37300-1
CA77.1 is an inducer of chaperone-mediated autophagy (CMA). It induces the formation of autophagic lysosomes in NIH3T3 cells expressing a CMA reporter when used at concentrations of 10, 20, and 30 µM. CA77.1 (20 µM) induces autophagic flux in NIH3T3 cells. In vivo, CA77.1 (30 mg/kg) reduces locomotor hyperactivity...
| Keywords: | N-[4-(6-chloro-2-quinoxalinyl)phenyl]-acetamide |
| Application: | Chaperone-mediated autophagy inducer |
| CAS | 2412270-22-3 |
| MW: | 297.7 D |
From 42.00€
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