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Item number: TGM-T63685-100mg

Description: DC-U4106 is a USP8-targeted inhibitor (Kd: 4.7 µM, IC50: 1.2 µM). DC-U4106 can use the ubiquitination pathway to promote the degradation of Eralpha. DC-U4106 inhibits the growth of tumor cells with low toxicity and can be used to study breast cancer. Target: Others. Smiles:...

CAS	2410534-62-0
MW:	525.56 D

From 3,766.00€ *

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DC-U4106

Item number: Cay41723-1

A USP8 inhibitor (IC50 = 1.2 µM), selective for USP8 over USP2 and USP7 (IC50s = 58.4 and >100 µM, respectively), induces apoptosis in, and inhibits colony formation by, MCF-7 cells from 1-5 µM, reduces tumor volume in an MCF-7 mouse xenograft model at 20 mg/kg. Formulation: A solid. InChI:...

Keywords:	8-[(3,5-dimethyl-1H-pyrazol-4-yl)oxy]-5,7-dihydroxy-2-[4-[4-(2-pyridinyl)-1-piperazinyl]phenyl]-4H-1-benzopyran-4-one
Application:	USP8 inhibitor
CAS	2410534-62-0
MW:	525.6 D

From 223.00€ *

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