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Item number: Cay44974-1

A selective estrogen receptor degrader, induces degradation of wild-type ERalpha and ERalphaY537S at 100 nM, reduces growth of ER+ T47D and MCF-7 cells (IC50s = 0.34 and 5.2 nM, respectively) but not MDA-MB-231 cells, reduces growth of ERalphaY537S -expressing T47D and MCF-7 cells (IC50s = 113 and 512 nM,...

Keywords:	(5R)-5-[4-[2-[3-(fluoromethyl)-1-azetidinyl]ethoxy]phenyl]-8-(trifluoromethyl)-H-[1]benzopyrano[4,3-c]quinolin-2-ol
Application:	Selective estrogen receptor degrader (SERD)
CAS	2408840-26-4
MW:	524.52 D

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Imlunestrant

Item number: TGM-T63674-100mg

Description: Imlunestrant is a selective, orally active estrogen receptor degrader (SERD) that can be used in ER+ and HER2 breast cancer studies. Target: Others. Smiles: OC1=CC=2C(=C3C(C=4C(O[C@@H]3C5=CC=C(OCCN6CC(CF)C6)C=C5)=CC(C(F)(F)F)=CC4)=CN2)C=C1

Application:	Antineoplastic
CAS	2408840-26-4
MW:	524.51 D

From 473.00€ *

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