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Item number: Cay44286-1

Edecesertib is an inhibitor of IL-1 receptor-associated kinase 4 (IRAK4, IC50 = 0. nM). It is selective for IRAK4 over a panel of 484 additional kinases at 1,000 nM. Edecesertib inhibits toll-like receptor 7 (TLR7) agonist-induced IFN-alpha production in isolated human whole blood (IC50 = 124 nM). Dietary...

Keywords:	GS-5718
Application:	IRAK4 inhibitor
CAS	2408839-73-4
MW:	435.46 D

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