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Item number: Cay42171-5

A RIPK2 inhibitor (IC50 = 5.3 nM), inhibits wild-type and R206H mutant ALK2 (IC50s = 47 and 22 nM, respectively), inhibits activin A-induced chondrogenic and osteogenic differentiation in ATDC-5 cells overexpressing ALKR206H at 0.5 µM, reduces the number of peritoneal lavage neutrophils and lymphocytes in a mouse...

Keywords:	OD36, Receptor-interacting Serine/Threonine Kinase 2 Inhibitor OD36,...
Application:	RIPK2 inhibitor
CAS	2387510-88-3
MW:	367.2 D

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OD36 hydrochloride

Item number: TGM-T61424-100mg

Description: OD36 hydrochloride (OD-36 hydrochloride) is a potent RIPK2 inhibitor with an IC50 of 5.3 nM.OD36 hydrochloride is a macrocyclic inhibitor that binds efficiently to the ATP pocket of the ALK2 kinase and effectively antagonizes mutant ALK2 signaling and osteogenic differentiation.OD36 hydrochloride...

Keywords:	OD-36 hydrochloride, OD 36 hydrochloride
CAS	2387510-88-3
MW:	367.23 D

From 1,222.00€ *

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