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Item number: Cay27815-1

BI-9321 is an antagonist of the histone-lysine N-methyltransferase NSD3 (IC50 = 0.203 µM in a time-resolved FRET (TR-FRET) assay). It selectively binds to the NSD3 PWWP1 domain over 14 other PWWP domains, including NSD2-PWWP1 and NSD3-PWWP2, at 100 µM. BI-9321 is also selective for NSD3 over 20 methyllysine-binding...

Keywords:	4-[5-(7-fluoro-4-quinolinyl)-1-methyl-1H-imidazol-4-yl]-3,5-dimethyl-benzenemethanamine, trihydrochloride
Application:	NSD3-PWWP1 antagonist
CAS	2387510-87-2
MW:	469,8 D

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