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Item number: Cay44114-1

Golcadomide is a cereblon (CRBN) E3 ligase modulator (CELMoD). It decreases protein levels of Ikaros family zinc finger protein 1 (IKZF1) and IFN regulatory factor 4 (IRF4) in JSC-1, BCBL-1, Daudi, and BL-41 lymphoma cells when used at a concentration of 0. µM and decreases the viability of these cells in a...

Keywords:	CC-99282,...
Application:	Cereblon modulator, CELMoD, antineoplastic, thalidomide derivative
CAS	2379572-34-4
MW:	535.58 D

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Golcadomide

Item number: TGM-T63771-100mg

Description: Golcadomide (CC-99282) is a orally active CRBN E3 ligase modulator that induces interactions between CRBN and its neo-substrate, recruiting the target disease-causing proteins and the E3 ubiquitin ligase.Golcadomide is used in the study of hematologic malignancies. Target: Ligand for E3 Ligase. Smiles:...

Keywords:	CC 99282, CC-99282, CC99282
Application:	Targets cereblon (CRBN)
CAS	2379572-34-4
MW:	535.57 D

From 155.00€ *

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