Dencatistat is an inhibitor of CTP synthase 1 (CTPS1, IC50 = 0.0093 µM), the enzyme that catalyzes the rate-limiting step in the conversion of UTP to CTP. It is selective for CTPS1 over CTPS2 (IC50 = 12.62 µM). Dencatistat inhibits the proliferation of nine cell lines derived from T cell-based cancers (IC50s = 2-183...