3 products were found matching "2375421-09-1"!
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SR-717 Lithium Salt
Item number: LKT-S680017.100
SR-717 Lithium salt is a STING agonist. SMILES: [Li+].C1=CC(=NN=C1C(=O)NC2=CC(=C(C=C2C(=O)[O-])F)F)N3C=CN=C3
| Keywords: | SR717 Lithium, lithium,4,5-difluoro-2-[(6-imidazol-1-ylpyridazine-3-carbonyl)amino]benzoate |
| Application: | STING agonist |
| CAS | 2375421-09-1 |
| MW: | 351.2 D |
From 99.00€
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SR-717
Item number: TGM-T8655-100mg
Description: SR-717 is a cGAMP analog, a non-nucleoside STING agonist that induces a "closed" activation conformation of STING. SR-717 has antitumor activity and promotes activation of immune cells and cross-presentation of antigens. Target: STING. Smiles: [Li+].[O-]C(=O)c1cc(F)c(F)cc1NC(=O)c1ccc(nn1)-n1ccnc1....
| Application: | STING agonist |
| CAS | 2375421-09-1 |
| MW: | 351.19 D |
From 75.00€
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SR 717 (lithium salt)
Item number: Cay31759-25
SR 717 is an agonist of stimulator of interferon genes (STING, EC50 = 2.1 µM in a reporter assay). It is selective for STING over a panel of 468 kinases. SR 717 (30 mg/kg, i.p.) increases plasma IFN-beta and IL-6 levels in mice. It also increases the intratumor frequency of CD69+CD8+ T cells, reduces tumor growth,...
| Keywords: | 4,5-difluoro-2-[[[6-(1H-imidazol-1-yl)-3-pyridazinyl]carbonyl]amino]-benzoic acid, monolithium salt |
| Application: | STING agonist |
| CAS | 2375421-09-1 |
| MW: | 351.2 D |
From 83.00€
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