Sulpiride is an antipsychotic that functions as an antagonist at D2/3 receptors and also upregulates and activates the GHB receptor. In vivo, sulpiride ameliorates increased impulsivity and attentional impairment in PFC-lesioned models of schizophrenia. Additionally, because dopamine inhibits prolactin release,...

Description: Levosulpiride (S-(-)-Sulpiride) is the (S)-enantiomer of sulpiride, which is a D2 receptor antagonist, an atypical antipsychotic drug of the benzamide class. Target: Dopamine Receptor. Smiles: C(NC[C@H]1N(CC)CCC1)(=O)C2=C(OC)C=CC(S(N)(=O)=O)=C2. References: Saporito F, et al. Int J Cardiol. 2014 Aug...