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Item number: TGM-T9258-100mg

Description: Aficamten is a Next-Generation Cardiac Myosin Inhibitor for the Treatment of Hypertrophic Cardiomyopathy. Target: Others. Smiles: CCc1nc(no1)-c1ccc2[C@@H](CCc2c1)NC(=O)c1cnn(C)c1

Application:	Targets myosin heavy chain 6/7 (MYH6_7)
CAS	2364554-48-1
MW:	337.38 D

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Aficamten

Item number: Cay36304-1

Aficamten is an inhibitor of cardiac myosin ATPase (IC50 = 1.26 µM for the bovine enzyme). It reduces fractional shortening in isolated rat cardiac ventricular myocytes (IC50 = 7.9 µM) and in rats in a dose-dependent manner.Formal Name:...

Keywords:	CK-274, CK-3773274, N-[(1R)-5-(5-ethyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl]-1-methyl-1H-pyrazole-4-carboxamide
Application:	Cardiac myosin ATPase inhibitor
CAS	2364554-48-1
MW:	337.4 D

From 132.00€ *

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