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Item number: Cay45748-1

CRBN-6-5-5-VHL is a proteolysis-targeting chimera (PROTAC) containing the cereblon (CRBN) inhibitor pomalidomide (Cay-19877) and the von Hippel-Lindau (VHL) E3 ligase ligand VH 032 (Cay-39982). It selectively induces the degradation of CRBN over Ikaros family zinc finger protein 1 (IKZF1) in MM.1S cells at 10-500...

Keywords:	Cereblon-6-5-5-VHL, Cereblon-6-5-5-von, CRBN-6-5-5-von, Hippel-Lindau,...
Application:	Cereblon (CRBN) degradation driving PROTAC
CAS	2362575-45-7
MW:	972.21 D

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