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Item number: Cay41681-10

DPTIP is an inhibitor of neutral sphingomyelinase 2 (nSMase2, IC50 = 30 nM). It is selective for nSMase2 over alkaline phosphatase (ALP) and acid sphingomyelinase (IC50s = >100 µM for both). DPTIP reduces viral yield in Vero and HeLa cells infected with West Nile virus (EC50s = 0.26 and 2.81 µM, respectively) or...

Keywords:	2,6-dimethoxy-4-[4-phenyl-5-(2-thienyl)-1H-imidazol-2-yl]-phenol, monohydrochloride
Application:	Neutral sphingomyelinase (Sphingomyelin phosphodiesterase 2, SMPD2) inhibitor
CAS	2361799-64-4
MW:	414.9 D

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