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OICR-12694
OICR-12694

Item number: Cay44288-1

OICR-12694 is an inhibitor of Bcl-6. It binds to the BTB domain on Bcl-6 (Kd = 5 nM in a surface plasmon resonance (SPR) assay). OICR-12694 decreases transcription of Bcl-6-targeted genes in a reporter assay using SU-DHL-4 cells (EC50 = 89 nM). It reduces the proliferation of Karpas-422 large B cell lymphoma cells...
Keywords: JNJ-65234637,...
Application: Bcl-6 inhibitor
CAS 2360625-97-2
MW: 645.04 D
From 76.00€ *
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OICR12694
OICR12694

Item number: TGM-T73333-100mg

Description: OICR12694 (JNJ-65234637) is an orally active B cell lymphoma 6 (BCL6) inhibitor. Target: Others. Smiles: O=C1C=2C(=CN(CC(NC=3C=C(N=C(F)C3Cl)N4[C@@H](C)CN(C)CC4)=O)C2N=C5N1CCC5)C6=CC(C(N)=O)=C(O)C(F)=C6F
Keywords: JNJ-65234637
CAS 2360625-97-2
MW: 645.03 D
From 2,864.00€ *
Review