Description: Procyanidin B3(B3) is a procyanidin dimer that is widely studied due to its high abundance in the human diet and antioxidant activity. Target: Histone Acetyltransferase. Smiles: O[C@H]1Cc2c(O)cc(O)c([C@H]3[C@H](O)[C@H](Oc4cc(O)cc(O)c34)c3ccc(O)c(O)c3)c2O[C@@H]1c1ccc(O)c(O)c1. References: Procyanidin B3...

Procyanidin B3 is a polyphenol flavonoid dimer of (+)-catechin (Cay-70940) that has been found in G. biloba and has diverse biological activities. It inhibits aggregation of amyloid-beta (1-42) (Abeta42, Cay-20574) with an IC50 value of 3.54 µM and destabilizes preformed Abeta42 fibrils (EC50 = 5.12 µM). Procyanidin...